Malnutrition Universal Screening Tool (MUST) scores predicts disease activity in patients with Crohn’s disease.

Adam Rahman ; Phil Williams ; Amindeep Sandhu ; Mahmoud Mosli

Volume 2016: (1)Page 1-5
DOI: https://doi.org.10.22433/2016/09/1

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  • Rahman, A. (2016). Malnutrition Universal Screening Tool (MUST) scores predicts disease activity in patients with Crohn’s disease.. 2016: (1), 1-5. Retrieved from http://canadianjournalofnutrition.ca/article/malnutrition-universal-screening-tool-must-scores-predicts-disease-activity-in-patients-with-crohns-disease/

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Abstract

Background:

Malnutrition in patients with inflammatory bowel disease (IBD) is common and under-recognized in patients with Crohn’s disease (CD) and ulcerative colitis (UC).

Aims:

We examined the relationship between nutritional risk and disease activity in outpatient inflammatory bowel disease patients, using the Malnutrition Universal Screening Tool (MUST).

Methods:

The study was conducted in outpatient IBD clinics in London, Ontario over two months. We examined the association between the MUST scores and the Harvey Bradshaw Index (HBI) and the PMI (Partial Mayo Score), for CD and UC, respectively. Logistic regression was used to examine associations between demographic data, disease characteristics and laboratory values with nutritional risk score.

Results:

There were a 154 patients were studied over a 2 month period. A high MUST score was strongly associated elevated Harvey Bradshaw Index scores (p=0.005) for patients with Crohn’s disease, but not with the Partial Mayo Index scores (p=0.597) for patients with ulcerative colitis. Nutritional risk scoring did not correlate with lower levels of disease activity. We noted significant associations in the odds of elevated nutritional risk and decreased albumin (OR 1.96, p<0.001), decreased Vitamin D (OR 1.51  p=0.032), and decreased creatinine (OR 1.47 , p=0.050).

Conclusions:

The MUST predicts disease activity in patients with Crohn’s disease but there is a floor effect. Further studies are required to determine if targeted treatment and monitoring of the nutritional state affects clinical outcomes in patients with CD/IBD

Ø  The authors declares no conflict of interest: A Rahman1,2,3,4, P. Williams1, A. Sandhu1, M. Mosli1

Ø  1Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada. 2 Lawson Health Research Institute, London, Ontario, Canada. 3Program of Experimental Medicine, Western University Department of Medicine.

Ø  Corresponding Author: Adam Rahman, MD MSc (EPID) FRCPC, Assistant Professor of Medicine, Division of Gastroenterology, Western University, adam.rahman@sjhc.london.on.ca, 268 Grosvenor St. London, Ontario, N6A 4V2

Ø  © Rahman et al. This is an open access article distributed under the terms of the Creative Common License BY NC

 

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  • Rahman, A. (2016). Malnutrition Universal Screening Tool (MUST) scores predicts disease activity in patients with Crohn’s disease.. 2016: (1), 1-5. Retrieved from http://canadianjournalofnutrition.ca/article/malnutrition-universal-screening-tool-must-scores-predicts-disease-activity-in-patients-with-crohns-disease/

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